n.

a variation in circumstances or fortune at different times in your life or in the development of something

"the project was subject to the usual vicissitudes of exploratory research"

mutability in life or nature (especially successive alternation from one condition to another)

Empathy and its vicissitudes
VICISSITUDES OF THE AFRICAN BIOMES IN THE LATE PLEISTOCENE
On some vicissitudes of insight in psycho-analysis.
Codes and their vicissitudes. Authors’ Response
Moods and their vicissitudes: Thoughts and feelings as information.
On human symbiosis and the vicissitudes of individuation.
Victual Vicissitudes: Consumer Deskilling and the (Gendered) Transformation of Food Systems
CONSTRUCTS AND THEIR VICISSITUDES IN EDUCATIONAL AND PSYCHOLOGICAL MEASUREMENT 1
Emotional autonomy versus detachment: revisiting the vicissitudes of adolescence and young adulthood
The Mediterranean benthos from late Miocene up to present: Ten million years of dramatic climatic and geologic vicissitudes